symptoms

What are symptoms of brain tumors?

The symptoms of brain tumors depend on tumor size, type, and location. Symptoms may be caused when a tumor presses on a nerve or damages a certain area of the brain. They also may be caused when the brain swells or fluid builds up within the skull.
Symptoms of a brain tumor can be many things including headaches. Headaches are the most common symptom of those facing this condition. The headache is the result of the pressure being placed on the area of the brain that is infected. The pressure is often placed on nerve endings found here as well as on the brain and the skull wall as well. When headaches change in their pattern, their intensity and come on gradually, then it could be a sign of a brain tumor.
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These are the most common symptoms of brain tumors:

  • Headaches (usually worse in the morning)

  • Nausea or vomiting

  • Changes in speech, vision, or hearing

  • Problems balancing or walking

  • Changes in mood, personality, or ability to concentrate

  • Problems with memory

  • Muscle jerking or twitching (seizures or convulsions)

  • Numbness or tingling in the arms or legs

These symptoms are not sure signs of a brain tumor. Other conditions also could cause these problems. Anyone with these symptoms should see a doctor as soon as possible. Only a doctor can diagnose and treat the problem.

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risk

Risk of brain tumor

The following risk factors are associated with an increased chance of developing a primary brain tumor:

  • Being male - In general, brain tumors are more common in males than females. However, meningiomas are more common in females.

  • Race - Brain tumors occur more often among white people than among people of other races.

  • Age - Most brain tumors are detected in people who are 70 years old or older. However, brain tumors are the second most common cancer in children. (Leukemia is the most common childhood cancer.) Brain tumors are more common in children younger than 8 years old than in older children.

  • Family history - People with family members who have gliomas may be more likely to develop this disease.

  • Being exposed to radiation or certain chemicals at work:
    • Radiation - Workers in the nuclear industry have an increased risk of developing a brain tumor.

    • Formaldehyde - Pathologists and embalmers who work with formaldehyde have an increased risk of developing brain cancer. Scientists have not found an increased risk of brain cancer among other types of workers exposed to formaldehyde.

    • Vinyl chloride - Workers who make plastics may be exposed to vinyl chloride. This chemical may increase the risk of brain tumors.
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causes

causes of brain tumor

No one knows the exact causes of brain tumors. Doctors can seldom explain why one person develops a brain tumor and another does not. However, it is clear that brain tumors are not contagious. No one can "catch" the disease from another person.

Research has shown that people with certain risk factors are more likely than others to develop a brain tumor. A risk factor is anything that increases a person's chance of developing a disease.


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Most brain tumors in children originate when a normal cell begins to grow abnormally and reproduce too rapidly. Eventually these cells develop into a mass called a tumor. The exact cause of this abnormal growth is unknown, though research continues on possible genetic and environmental causes.

Some kids are more susceptible to developing brain tumors due to certain genetic conditions. Diseases such as neurofibromatosis, von Hippel-Lindau disease, Li-Fraumeni syndrome, and retinoblastoma are all associated with a higher risk of brain tumors.

brain tumor

What Is a Brain Tumor?

A tumor is any mass caused by abnormal or uncontrolled growth of cells. Tumors in the brain are categorized according to several factors, including where they're located, the type of cells involved, and how quickly they're growing.

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Medical terms doctors may use to describe brain tumors include:
Primary vs. secondary: Primary brain tumors originate in the brain. Secondary brain tumors are made up of cells that have spread (metastasized) to the brain from somewhere else in the body. In children, most brain tumors are primary. The opposite is true in adults.
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Benign vs. malignant: Benign tumors are slow-growing, noncancerous, and do not spread to surrounding tissue. Malignant tumors, on the other hand, are cancerous. Fast-growing and aggressive, they can invade nearby tissue and also are more likely to recur after treatment. Though malignancies are generally associated with a worse outlook, in the brain, benign tumors can be just as serious, especially if they're in a critical location (such as the brain stem, which controls breathing) or grow large enough to press on vital brain structures.
  • Localized vs. invasive: A localized tumor is confined to one area and is generally easier to remove, as long as it's in an accessible part of the brain. An invasive tumor has spread to surrounding areas and is more difficult to remove completely.
  • Grade: The grade of a tumor indicates how aggressive it is. Today, most medical experts use a system designed by the World Health Organization (WHO) to identify brain tumors and help make a prognosis. The lower the grade, the less aggressive the tumor and the greater the chance for a cure. The higher the grade, the more aggressive the tumor and the harder it may be to cure.

brain

What is the brain?

he brain is a soft, spongy mass of tissue. It is protected by the bones of the skull and three thin membranes called meninges. Watery fluid called cerebrospinal fluid cushions the brain. This fluid flows through spaces between the meninges and through spaces within the brain called ventricles. A network of nerves carries messages back and forth between the brain and the rest of the body. Some nerves go directly from the brain to the eyes, ears, and other parts of the head. Other nerves run through the spinal cord to connect the brain with the other parts of the body. Within the brain and spinal cord, glial cells surround nerve cells and hold them in place.
Picture of the Brain and Nearby Structures
The brain and nearby structures

The brain directs the things we choose to do (like walking and talking) and the things our body does without thinking (like breathing). The brain is also in charge of our senses (sight, hearing, touch, taste, and smell), memory, emotions, and personality.

The three major parts of the brain control different activities:

  • Cerebrum - The cerebrum is the largest part of the brain. It is at the top of the brain. It uses information from our senses to tell us what is going on around us and tells our body how to respond. It controls reading, thinking, learning, speech, and emotions.

The cerebrum is divided into the left and right cerebral hemispheres, which control separate activities. The right hemisphere controls the muscles on the left side of the body. The left hemisphere controls the muscles on the right side of the body.

  • Cerebellum - The cerebellum is under the cerebrum at the back of the brain. The cerebellum controls balance and complex actions like walking and talking.

  • Brain Stem - The brain stem connects the brain with the spinal cord. It controls hunger and thirst. It also controls breathing, body temperature, blood pressure, and other basic body functions.

Fatcs

Cancer Factors

octors often cannot explain why one person develops cancer and another does not. But research shows that certain risk factors increase the chance that a person will develop cancer. These are the most common risk factors for cancer:
  • Growing older


  • Tobacco


  • Sunlight


  • Ionizing radiation


  • Certain chemicals and other substances


  • Some viruses and bacteria


  • Certain hormones


  • Family history of cancer


  • Alcohol


  • Poor diet, lack of physical activity, or being overweight
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Acne Treatments

Top 3 Acne Treatments

90% of teenagers have acne. If acne is left untreated, many of these teenagers have acne even into adulthood. And, with so many junk acne products out there, it's often difficult to find acne treatments that work.

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This website analyzes the best acne treatments for both adults and teenagers currently on the market. Each acne treatment was reviewed based on three standards:

  1. Exposed
  2. ClearPores
  3. Zenmed

Herbal Medicine

Best Herbal Medicine For Acne Removal

ACNE-R

Acne-R is a guaranteed treatment for all forms of acne. It removes pimples and blackheads from any part of body. Acne-R also cures all kinds of boils, by drying extra serums produced in the blood. It also helps to remove ir-regularities of menstrual cycle in females (specially when taken with Leauchoren). Acne-R can be used by men and females of all ages and it has no side effects at all. It is an all natural and herbal product.
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Around three-quarters of all teenagers and young adults suffer from acne. However, men and women in their 30s and 40s can also suffer.The exact cause of acne remains unclear but more is known about how the spots that are part of acne form. And there are more and more treatments to help deal with this distressing condition.
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About Acne-R:

Acne-R is a herbal medicine, formulated to cure all forms of acne. All ingredients are extracted from 100% naturally occurring herbs, without any chemical alterations. Each tablet contains the following ingredients, processed and blended a palatable base:

Tukham-Jaman
Dried Karaila
Mundi Booty
Swertia Chirata
FumariaOfficinalis

Lycopodium, Clavatum
Berberis Aristata DC. Ext.
Terminalia Chebula
Zizyphus Vulgaris
Terminalia Chebula

medifast

What is Medifast

Medifast is more than a diet plan. Medifast is a way to reclaim your health through clinically formulated meal replacement foods that have been developed, improved and proven for over 20 years. Through the take shape for life program, Medifast offers you complete support with your own personal health advisor. As nationally certified Presidential health advisors, here at MakeMeThinner we also offer a forum, newsletter, a toll free hotline you can call whenever you need an encouraging word or help of any kind with the Medifast line of products.

Our goal is to bring you the safest, easiest, and most important, the most successful experience using Medifast products. We are constantly adding to, changing and improving our method for introducing and educating people about the Medifast products and Medifast health plans. If you think of any way we can improve our services for you while on the plan, please email or call us with your ideas.

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medifast

Medifast weight lose for women

The Medifast 5 & 1 Plan helps women lose weight quickly, leading to tremendous improvements in overall health. Medifast is much more than the traditional, fad diets that may have failed you in the past. Medifast helps you lose the weight – and teaches you how to keep it off! The Medifast program is convenient, portion-controlled, and simple to follow. You’ll see and feel results in the first week!

Most women start by ordering the Medifast for Women 4-Week Package. With this package you receive the most popular Medifast Meals – and save over $30!

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exercise

Top 10 weight lose exercise

Just as eating healthy, it’s important to do some exercise as well. The best exercises will contain a cardio aspect and a toning aspect, as this will allow you to see the results fastest.

Here are my top 10 weight loss exercises, and how many calories they burn!

1. step aerobics:

Calories Burnt: 800 cal/hr

This mainly targets your legs, hips and bum, which are often the areas that women most want to tone. Doing an hour a day, split into two half an hour sessions, will ensure that you see results within 2 weeks.

Another very similar exercise is bench presses, which go very well in sets with step aerobics. I found it really hard to do them to start with, so make sure you’re doing them right or you’ll see no results!

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2. Bicycling:

Calories Burnt: 500 – 1000 cal/hr

Depending on how fast you go, this can be a real calorie burner. Riding outside is always enjoyable, but if you’re a little more time restricted, invest in a good quality exercise bike.

This is my favorite calorie burner, because it’s so easy to do. How about riding while watching the TV? I find that cycling through Eastenders keeps me distracted, but working hard.

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3. Swimmin:

Calories Burnt: 800 cals/hr

Doing lengths up and down the pool for an hour will burn off 800 calories, and also tone almost all of your body. Stay motivated by giving yourself half an hour extra to make use of the Jacuzzi when you’ve finished!

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4. Racquetball:

Calories Burnt: 800 cals/hr

The side to side running involved in this is a great cardio workout, and will also help to tone your thighs and legs. I also find this to be much more sociable, which keeps me working out for longer and stops me skiving my gym sessions!

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5. Elliptical Burner:

Calories Burnt: 600 cals/hr

This is brilliant cardio, and also helps to build strong muscles, as well as toning the stomach. I personally find Elliptical Burner really boring, so I split my session into ten minute bursts and do them throughout the day, and I find that listening to some upbeat music really helps as well.

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Exercise

Weight Loss Exercise Programs

Exercising for weight loss doesn't have to be hard, just consistent. If you can get some form of exercise most days of the week, you will not only lose weight, you'll also be fitter. More importantly though, you'll live longer! Just a small amount of exercise can reduce your risk of heart disease significantly.

I have provided some exercise programs here for beginners. Choose one to start with then as you get used to that walking program, pick another and mix them up. Remember, start out at a low intensity and build it up as your body adapts. Any exercise is good so have a think about what you enjoy doing. Have a look at our Goal Setting, and our Motivation sections. Incorporate those with the following programs and you will achieve your weight loss goals in no time!

Program 1

  • Start by exercising for 10 minutes, 6 days per week, or 20 minutes, 3 days per week. If you can do 60 minutes then even better.

  • Always start with a light walk to warm up, and then increase the pace of your walk.

Program 2

  • Warm up and stretch for 5-10 minutes.

  • Power walk for 5 minutes, slow walk for 2 minutes.

  • Repeat for duration of your walk.

  • Always complete a warm down before finishing the session.

Woman practicing yoga photo

How to lose weight

The most effective method for weight loss is reducing the number of calories you consume while increasing the number of calories you burn through physical activity. To lose 1 pound, you need an expenditure of approximately 3,500 calories. You can achieve this either by cutting back on your food intake, by increasing physical activity, or ideally, by doing both.
For example, if you consume 500 extra calories per day for one week without changing your activity level, you will gain 1 pound in weight (seven days multiplied by 500 calories equals 3,500 calories, or the number of calories resulting in a 1-pound weight gain). Likewise, if you eat 500 fewer calories each day for a week or burn 500 calories per day through exercise for one week, you will lose 1 pound.
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Finding a Healthy Weight

Weight loss is a tricky topic. Lots of people are unhappy with their present weight, but most aren't sure how to change it — and many would be better off staying where they are. You may want to look like the models or actors in magazines and on TV, but those goals might not be healthy or realistic for you. Besides, no magical diet or pill will make you look like someone else.http://quick-weightloss-diet.info/wp-content/uploads/2009/03/quick-weight-loss-33.jpg

So what should you do about weight control?

Being healthy is really about being at a weight that is right for you. The best way to find out if you are at a healthy weight or if you need to lose or gain weight is to talk to a doctor or dietitian, who can compare your weight with healthy norms to help you set realistic goals. If it turns out that you can benefit from weight loss, then you can follow a few of the simple suggestions listed below to get started.

Weight management is about long-term success. People who lose weight quickly by crash dieting or other extreme measures usually gain back all (and often more) of the pounds they lost because they haven't permanently changed their habits.

Complications

Complications of acne

There are a number of things that can make your acne worse. These include the following.
  • If you pick and squeeze the spots, it may cause further inflammation and scarring.
  • Excessive production of male hormones may cause acne. For example, testosterone from conditions such as polycystic ovary syndrome.
Acne Treatments Before Picture 1

  • Some contraceptive pills may make acne worse. This is due to the type of progestogen hormone in some pills. However, some other types of contraceptive pills can improve acne (see Treatments). Ask your GP for advice about which contraceptive pill to take.
  • Some cosmetic products such as moisturisers can make acne worse if they are greasy.

Types

Types of acne

Acne Vulgaris is the most common form of acne which includes several types of pimples. These acne lesions include blackheads, whiteheads, papules, pustules, nodules and cysts.
Whiteheads

Whiteheads result when a pore is completely blocked, trapping sebum (oil), bacteria, and dead skin cells, causing a white appearance on the surface. These types of acne lesions sometimes seem to be begging to be popped.
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Make sure you read about how to pop a pimple before you attempt this. Whiteheads are normally quicker in life cycle than blackheads.
Blackheads
Blackheads result when a pore is only partially blocked, allowing some of the trapped sebum (oil), bacteria, and dead skin cells to slowly drain to the surface. The black color is not caused by dirt. Rather, it is a reaction of the skin's own pigment, melanin, reacting with the oxygen in the air.

Acne picture - blackhead pimple.

A blackhead tends to be a stable structure, and can often take a long time to clear.
Papules
A papule is defined as a small (5 millimeters or less), solid lesion slightly elevated above the surface of the skin. A group of very small papules and microcomedones may be almost invisible but have a "sandpaper" feel to the touch. A papule is caused by localized cellular reaction to the process of acne. This photo shows papules and comedones on the face of an acne patien

Rosacea Red Nose

Acne information

Acne:
Localized skin inflammation as a result of overactivity of the oil glands at the base of hair follicles.Acne happens when oil (sebaceous) glands come to life around puberty, when these glands are stimulated by male hormones that are produced in the adrenal glands of both boys and girls.

The oil glands, which are located just beneath the skin, continuously produce and secrete oil through openings in the skin. The oil lubricates and protects the skin. Under certain circumstances, cells that are close to the openings of the oil glands block the openings. This causes a buildup of oil underneath the skin.

Herbs

Herbs for Oily Skin

Aloe vera has excellent healing properties. Apply aloe vera gel topically, as needed.

Burdock root, chamomile, horsetail, oat straw, and thyme nourish the skin.

Lavender is very good for oily skin. Mist your skin with lavender water several times daily.

A facial sauna using lemongrass, licorice root, and rosebuds is good for oily skin.

Two or three times a week, simmer a total of 2 to 4 tablespoons of dried or fresh herbs in 2 quarts of water.

When the pot is steaming, place it on top of a trivet or thick potholder on a table, and sit with your face at a comfortable distance over the steam for fifteen minutes.

You can use a towel to trap the steam if you wish.

After fifteen minutes, splash your face with cold water and allow your skin to air dry or pat it dry with a towel.

After the sauna, you can allow the herbal water to cool and save it for use as a toning lotion to be dabbed on your face with a cot- ton ball after cleansing.

skin care

Natural Skincare

Half an hour before taking your bath apply on your face half teaspoon each of lime and cucumber juice mixed together.

If your skin is excessively oily, mix in a few drops of eau de cologne. This not only helps keep oiliness away but also helps in refining the pores of the skin by acting as astringent, thereby preventing acne.

To prevent the problem of your makeup becoming patchy either on the forehead, chin or nose due to excessive oiliness in these areas, apply a little cucumber juice on the excessively oily parts of your face, dry thoroughly and then apply your makeup.

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If your whole face turns patchy after makeup is applied on it, then apply equal parts of lime juice and witch-hazel. Dry well before putting on your makeup.

Choose an astringent that contains acetone, which is known for dissolving oil. Strong astringents will do more harm than good, stimulating an overproduction of oil.

To clear away excess oil, use a clay or mud mask. Blend together well 1 teaspoon green clay powder and 1 teaspoon raw honey. Apply the mixture to your face, avoiding the eye area. Leave it on for fifteen minutes, then rinse well with lukewarm water. Do this at least three times a week--or more.

Once or twice daily, mix equal parts of lemon juice and water together. Pat mixture on your face and allow it to dry, then rinse with warm water. Follow with a cool-water rinse.

oily skin

Oily skin
Oily skin is shiny, thick and dull colored. Often a chronically oily skin has coarse pores and pimples and other embarrassing blemishes. It is prone to blackheads. In this type of skin, the oil producing sebaceous glands are overactive and produce more oil than is needed. The oil oozes and gives the skin a greasy shine. The pores are enlarged and the skin has a coarse look.

Causes of Oily Skin

  • Heredity

  • Diet
  • Hormone levels
  • Pregnancy
  • Birth control pills
  • Cosmetics you use
  • Humidity and hot weather

Because of the hormonal shifts of adolescence, oily skin is common in teenagers, but it can occur at any age. In general, skin tends to become dryer with age. The flow of sebum or oil increases during adolescence and starts decreasing with age. During pregnancy and menopause, hormonal imbalances can also upset the oil balance and increase the activity of sebaceous glands.

Many people have skin that is oily only in certain areas and dry or normal in others, a condition known as combination skin.

Skin Care for Oily Skin

The great advantage of oily skin is that it ages at a slower rate than other skin types.

Oily skin needs special cleansing with plenty of hot water and soap to prevent the pores from being clogged. Avoid harsh products that strip your skin of oil and encourage flakiness. They can cause a reaction known as reactive seborrhoea, where the oil glands work overtime to compensate for the loss of natural oils.

Avoid skincare products that leave your skin feeling taut and dehydrated. They cause the upper layers of the skin to shrink. This restricts oil flow through the pores leading to blockages and breakouts.

To cleanse oily skin, use oil-based products as they dissolve sebum effectively. Opt for oil-free moisturizers to maintain a shine-free complexion.

Keep your skin very clean. Limit washing your face to two or three times a day. Too much washing will stimulate your skin to produce more oil.

Choose your cleanser with care. Avoid heavy cleansing creams. Avoid the use of harsh soaps or cleansers. Use a pure soap with no artificial additives. Try an antibacterial cleansing lotion or a lightly medicated soap, and use it in combination with a water rich in minerals, not tap water. Do not use cleansers or lotions that contain alcohol. After cleansing, apply a natural oil-free moisturizer to keep the skin supple.

Use hot water when washing your face. Hot water dissolves skin oil better than lukewarm or cold water.

If your skin is extremely oily, three or four daily cleansings may be in order and little or no moisturizing necessary before you are 30 years old. After that point, the skin around your eyes and mouth and on your throat may benefit from a nightly moisturizing, plus a mere touch of moisturizer in the morning.

When cleansing, massage your face well with your fingertips, using an upward and outward motion. Be careful not to rub soap into the skin; it can clog pores.

If your oily skin is scaly, you can often correct the problem by using a deep-cleaning exfoliant on alternate nights, and following the treatment with a light coating of moisturizer.

Try using a clay or mud mask. If you have sensitive skin, use white or rose-colored clays.

Use a light antiseptic night cream from time to time if you wish, and apply a clarifying mask one or two times a week.

Choose cosmetic and facial care products specifically designed for oily skin.

Before applying makeup, use an antiseptic day cream with active ingredients that diminish sebaceous secretions. Look for benzyl peroxide in the list of active ingredients.

Use a light antiseptic night cream from time to time if you wish, and apply a clarifying mask one or two times a week.

Skin information

Normal skin
Normal skin is completely healthy. In youth it is smooth, fine pores, and soft, but with age it becomes dry, wrinkled, and marked with the so-called "age spots." Between these two normal conditions there are short periods of change and irritations of the normal skin caused by hormonal changes, illness, and lifestyles.

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Normal skin needs no extensive special care now, but one should think of tomorrow. Normal skin can be treated simply with a mild cleansing lotion, toner and a alpha hydroxy acid cream in remove dead skin and an facial scrub to reduce the effects of a bad environment. Suitable aromapathic essential oils for normal skin care are:chamomile, comfrey, rose hips, and sage.

Treatments

Treatment of skin cancer
Specific treatment for skin cancer will be determined by your physician based on:
  • your age, overall health, and medical history
  • extent of the disease
  • your tolerance for specific medications, procedures, or therapies
  • expectations for the course of the disease
  • your opinion or preference







There are several kinds of treatments for skin cancer, including the following:

surgery

Surgery is a common treatment for skin cancer -- used about 90 percent of the time, and often includes the following procedures:
    1. cryosurgery - freezing the tumor, which kills cancer cells.

    2. electrodesiccation and curettage - burning the lesion and removing it with a sharp instrument.

    3. grafting - uses a skin graft to replace skin that is damaged when cancer is removed.

    4. laser therapy - using a narrow beam of light to remove cancer cells.

    5. Mohs micrographic surgery - removing the cancer and as little normal tissue as possible. During this surgery, the physician removes the cancer and then uses a microscope to look at the cancerous area to make sure no cancer cells remain.

    6. simple excision - cutting the cancer from the skin along with some of the healthy tissue around it.

Risk

Risk of skin cancer:
These factors may increase your risk of skin cancer:
  • Fair skin. Having less pigment (melanin) in your skin provides less protection from damaging UV radiation. If you have blond or red hair, light-colored eyes, and you freckle or sunburn easily, you're much more likely to develop skin cancer than is a person with darker features.
  • A history of sunburns. Every time you get sunburned, you damage your skin cells and increase your risk of developing skin cancer. After a sunburn, your body works to repair the damage. Having multiple blistering sunburns as a child or teenager increases your risk of developing skin cancer as an adult. Sunburns in adulthood also are a risk factor.












  • Excessive sun exposure. Anyone who spends considerable time in the sun may develop skin cancer, especially if your skin isn't protected by sunscreen or clothing. Tanning also puts you at risk. A tan is your skin's injury response to excessive UV radiation.
  • Sunny or high-altitude climates. People who live in sunny, warm climates are exposed to more sunlight than are people who live in colder climates. Living at higher elevations, where the sunlight is strongest, also exposes you to more radiation.
  • Moles. People who have many moles or abnormal moles called dysplastic nevi are at increased risk of skin cancer. These abnormal moles — which look irregular and are generally larger than normal moles — are more likely than others to become cancerous. If you have a history of abnormal moles, watch them regularly for changes.

Symptoms

Symptoms of skin cancer

Different types of skin cancer can look different:

Non-melanomas such as a BCC, for example, can start as a small red, pink or shiny lump. SCCs often appear as small scaly or hard areas of skin with a red or pink base.

Melanoma usually starts as a dark spot or mole on your skin. If a melanoma spreads to other parts of your body, you can develop other symptoms such as swollen lymph nodes (glands throughout your body that are part of your immune system).

Symptoms that may indicate skin cancer include any mole or lesion that:

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  • gets bigger - especially over 7mm (a quarter of an inch) in diameter
  • changes shape - look for an irregular edge
  • changes colour - if it darkens, becomes patchy or multishaded
  • becomes inflamed
  • is itchy or painful
  • bleeds or is crusty

These symptoms don't necessarily mean you have skin cancer, but if you have any of them you should visit your GP for advice.

causes

Causes of skin cancer

Ultraviolet (UV) light exposure, most commonly from sunlight, is overwhelmingly the most frequent cause of skin cancer.

Other important causes of skin cancer include the following:

  • Use of tanning booths

  • Immunosuppression-impairment of the immune system, which protects the body from foreign entities, such as germs or substances that cause an allergic reaction. This may occur as a consequence of some diseases or can be due to medications prescribed to combat autoimmune diseases or prevent organ transplant rejection.

  • Exposure to unusually high levels of x rays

  • Contact with certain chemicals-arsenic (miners, sheep shearers, and farmers), hydrocarbons in tar, oils, and soot (may cause squamous cell carcinoma)

The following people are at the greatest risk:

  • People with fair skin, especially types that freckle, sunburn easily, or become painful in the sun

  • People with light (blond or red) hair and blue or green eyes
  • People who have already been treated for skin cancer

  • People with numerous moles, unusual moles, or large moles that were present at birth

  • People with close family members who have developed skin cancer

  • People who had at least one severe sunburn early in life

Basal cell carcinomas and squamous cell carcinomas are more common in older people. Melanomas are more common in younger people. For example, melanoma is the most common cancer in people 25-29 years of age.

Types

Types of skin cancer

Three types of skin cancer account for nearly 100% of all diagnosed cases. Each of these three cancers begins in a different type of cell within the skin, and each cancer is named for the type of cell in which it begins. Skin cancers are divided into one of two classes - nonmelanoma skin cancers and melanoma. Melanoma is the deadliest form of skin cancer.

The different types of skin cancer are:

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Basal cell carcinoma (BCC):
The most common cancer in humans, BCC develops in more than 1 million people every year in the United States alone. About 80% of all skin cancers are BCC, a cancer that develops in the basal cells - skin cells located in the lowest layer of the epidermis. BCC can take several forms. It can appear as a shiny translucent or pearly nodule, a sore that continuously heals and then re-opens, a pink slightly elevated growth, reddish irritated patches of skin, or a waxy scar. Most BCCs appear on skin with a history of exposure to the sun, such as the face, ears, scalp, and upper trunk. These tumors tend to grow slowly and can take years to reach ½ inch in size. While these tumors very rarely metastasize (cancer spreads to other parts of the body), dermatologists encourage early diagnosis and treatment to prevent extensive damage to surrounding tissue.

skin cancer

What is skin cancer

Skin cancer is the most common form of cancer in the United States. The two most common types are basal cell cancer and squamous cell cancer. They usually form on the head, face, neck, hands and arms. Another type of skin cancer,melanoma , is more dangerous but less common.

Anyone can get skin cancer, but it is more common in people who

  • Spend a lot of time in the sun or have been sunburned
  • Have light-colored skin, hair and eyes
  • Have a family member with skin cancer
  • Are over age 50

You should have your doctor check any suspicious skin markings and any changes in the way your skin looks. Treatment is more likely to work well when cancer is found early. If not treated, some types of skin cancer cells can spread to other tissues and organs.

Treatment

Treatment of gall stones

Surgery

Surgery to remove the gallbladder is the most common way to treat symptomatic gallstones. (Asymptomatic gallstones usually do not need treatment.) Each year more than 500,000 Americans have gallbladder surgery. The surgery is called cholecystectomy.

The standard surgery is called laparoscopic cholecystectomy. For this operation, the surgeon makes several tiny incisions in the abdomen and inserts surgical instruments and a miniature video camera into the abdomen. The camera sends a magnified image from inside the body to a video monitor, giving the surgeon a closeup view of the organs and tissues. While watching the monitor, the surgeon uses the instruments to carefully separate the gallbladder from the liver, ducts, and other structures. Then the cystic duct is cut and the gallbladder removed through one of the small incisions.

Because the abdominal muscles are not cut during laparoscopic surgery, patients have less pain and fewer complications than they would have had after surgery using a large incision across the abdomen. Recovery usually involves only one night in the hospital, followed by several days of restricted activity at home.

If the surgeon discovers any obstacles to the laparoscopic procedure, such as infection or scarring from other operations, the operating team may have to switch to open surgery. In some cases the obstacles are known before surgery, and an open surgery is planned. It is called "open" surgery because the surgeon has to make a 5- to 8-inch incision in the abdomen to remove the gallbladder. This is a major surgery and may require about a 2- to 7-day stay in the hospital and several more weeks at home to recover. Open surgery is required in about 5 percent of gallbladder operations.

The most common complication in gallbladder surgery is injury to the bile ducts. An injured common bile duct can leak bile and cause a painful and potentially dangerous infection. Mild injuries can sometimes be treated nonsurgically. Major injury, however, is more serious and requires additional surgery.

If gallstones are in the bile ducts, the surgeon may use ERCP in removing them before or during the gallbladder surgery. Once the endoscope is in the small intestine, the surgeon locates the affected bile duct. An instrument on the endoscope is used to cut the duct, and the stone is captured in a tiny basket and removed with the endoscope. This two-step procedure is called ERCP with endoscopic sphincterotomy.

Occasionally, a person who has had a cholecystectomy is diagnosed with a gallstone in the bile ducts weeks, months, or even years after the surgery. The two-step ERCP procedure is usually successful in removing the stone.

Nonsurgical Treatment

Nonsurgical approaches are used only in special situations such as when a patient's condition prevents using an anesthetic and only for cholesterol stones. Stones recur after nonsurgical treatment about half the time.

  • Oral dissolution therapy. Drugs made from bile acid are used to dissolve the stones. The drugs, ursodiol (Actigall) and chenodiol (Chenix), work best for small cholesterol stones. Months or years of treatment may be necessary before all the stones dissolve. Both drugs cause mild diarrhea, and chenodiol may temporarily raise levels of blood cholesterol and the liver enzyme transaminase.
  • Contact dissolution therapy. This experimental procedure involves injecting a drug directly into the gallbladder to dissolve stones. The drug methyl tert butyl can dissolve some stones in 1 to 3 days, but it must be used very carefully because it is a flammable anesthetic that can be toxic. The procedure is being tested in patients with symptomatic, noncalcified cholesterol stones.
  • Extracorporeal shockwave lithotripsy (ESWL). This treatment uses shock waves to break up stones into tiny pieces that can pass through the bile ducts without causing blockages. Attacks of biliary colic (intense pain) are common after treatment, and ESWL's success rate is not very high. Remaining stones can sometimes be dissolved with medication.

Risk

Riskof gall stones

People at risk for gallstones include
  • women—especially women who are pregnant, use hormone replacement therapy, or take birth control pills
  • people over age 60
  • American Indians
  • Mexican Americans
  • overweight or obese men and women
  • people who fast or lose a lot of weight quickly
  • people with a family history of gallstones
  • people with diabetes
  • people who take cholesterol-lowering drugs.

symptoms

Symptoms of gallstones

As gallstones move into the bile ducts and create blockage, pressure increases in the gallbladder and one or more symptoms may occur. Symptoms of blocked bile ducts are often called a gallbladder “attack” because they occur suddenly. Gallbladder attacks often follow fatty meals, and they may occur during the night. A typical attack can cause
  • steady pain in the right upper abdomen that increases rapidly and lasts from 30 minutes to several hours
  • pain in the back between the shoulder blades
  • pain under the right shoulder
Notify your doctor if you think you have experienced a gallbladder attack. Although these attacks often pass as gallstones move, your gallbladder can become infected and rupture if a blockage remains.
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People with any of the following symptoms should see a doctor immediately:

  • prolonged pain—more than 5 hours
  • nausea and vomiting
  • fever—even low-grade—or chills
  • yellowish color of the skin or whites of the eyes
  • clay-colored stools

Many people with gallstones have no symptoms; these gallstones are called “silent stones.” They do not interfere with gallbladder, liver, or pancreas function and do not need treatment.

causes

causes of gall bladder stones

Scientists believe cholesterol stones form when bile contains too much cholesterol, too much bilirubin, or not enough bile salts, or when the gallbladder does not empty completely or often enough. The reason these imbalances occur is not known.

The cause of pigment stones is not fully understood. The stones tend to develop in people who have liver cirrhosis, biliary tract infections, or hereditary blood disorders—such as sickle cell anemia—in which the liver makes too much bilirubin.

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gallstones

What is gallstones

Gallstones are small, pebble-like substances that develop in the gallbladder. The gallbladder is a small, pear-shaped sac located below your liver in the right upper abdomen. Gallstones form when liquid stored in the gallbladder hardens into pieces of stone-like material. The liquid—called bile—helps the body digest fats. Bile is made in the liver, then stored in the gallbladder until the body needs it. The gallbladder contracts and pushes the bile into a tube—called the common bile duct—that carries it to the small intestine, where it helps with digestion.

Bile contains water, cholesterol, fats, bile salts, proteins, and bilirubin—a waste product. Bile salts break up fat, and bilirubin gives bile and stool a yellowish-brown color. If the liquid bile contains too much cholesterol, bile salts, or bilirubin, it can harden into gallstones.

Illustration of the biliary system, showing the liver, gallbladder, pancreas, and the duodenum with the appendant ducts.
The two types of gallstones are cholesterol stones and pigment stones. Cholesterol stones are usually yellow-green and are made primarily of hardened cholesterol. They account for about 80 percent of gallstones. Pigment stones are small, dark stones made of bilirubin. Gallstones can be as small as a grain of sand or as large as a golf ball. The gallbladder can develop just one large stone, hundreds of tiny stones, or a combination of the two.
The two types of gallstones are cholesterol stones and pigment stones. Cholesterol stones are usually yellow-green and are made primarily of hardened cholesterol. They account for about 80 percent of gallstones. Pigment stones are small, dark stones made of bilirubin. Gallstones can be as small as a grain of sand or as large as a golf ball. The gallbladder can develop just one large stone, hundreds of tiny stones, or a combination of the two.

Self-Care

Treatment of kidney stones

Self-Care at Home:
  • Prevention is always the preferable way to treat kidney stones. Remaining well hydrated and keeping the urine dilute will help prevent kidney stones from forming.

  • Those who have never passed a kidney stone may not appreciate the severity of the symptoms. There is little a person can do with debilitating pain and vomiting other than seek emergency care. If this is the first episode and no previous diagnosis has been established, it is important to be seen by a physician as well. For those who have a history of stones, then home therapy may be appropriate. Most kidney stones, given time, will pass on their own, and treatment is directed towards symptom control. The patient should be instructed to consume oral fluids. Ibuprofen can be used as an anti-inflammatory agent, and if further pain medication is needed, contacting the primary care provider may allow stronger narcotic pain medication to be prescribed.

  • Please note, if there is fever associated with the symptoms of a kidney stone, this becomes a more urgent problem, and medical care should be accessed immediately.

Symptoms

Symptoms of kidney stones

Many kidney stones don't move and are too small to cause any symptoms. However, if a kidney stone causes a blockage, or moves into your ureter, you may:

  • have severe pain or ache on one or both sides of your back
  • get sudden spasms of excruciating pain - this usually starts in the back below your ribs, before radiating around your abdomen, and sometimes to your groin and genitals
  • have bloody or cloudy urine
  • feel sick or vomit
  • feel a frequent urge to urinate, or a burning sensation during urination
  • get fever and chills
Illustration the position of the kidneys and surrounding structures

You can also have these symptoms if you have a urinary tract infection (UTI) or cystitis. If you have one or more of these symptoms, you should ask your GP for advice.

The pain of kidney stones - referred to as 'renal colic' - can be very severe. It begins as soon as the stone becomes stuck in the ureter and tends to come in waves. It's not usually associated with the size of the kidney stone - sometimes small stones can cause more pain than very large ones.

Small kidney stones are usually passed out of the body within a day or so and mostly within four weeks of the onset of symptoms. The bigger the stone the less likely it is to pass out of the body spontaneously. Stones greater than 5mm (a quarter of an inch) in diameter are the least likely to pass without medical help.

If you're pregnant and have any symptoms of kidney stones, see your GP straight away.

What do my kidneys do?

Your kidneys are bean-shaped organs, each about the size of your fist. They are located near the middle of your back, just below the rib cage, one on each side of the spine. The kidneys are sophisticated trash collectors. Every day, your kidneys process about 200 quarts of blood to sift out about 2 quarts of waste products and extra water. The wastes and extra water become urine, which flows to your bladder through tubes called ureters. Your bladder stores urine until
you go to the bathroom.

Image of kidneys, ureters, bladder and urethra system.

The wastes in your blood come from the normal breakdown of active muscle and from the food you eat. Your body uses the food for energy and self-repair. After your body has taken what it needs from the food, wastes are sent to the blood. If your kidneys did not remove these wastes, they would build up in the blood and damage your body.

In addition to removing wastes, your kidneys help control blood pressure. They also help make red blood cells and keep your bones strong.

Causes

Causes of kidney stones

Your kidneys are two bean-shaped organs, each about the size of your fist. They're located in back of your abdomen on each side of your spine, and their main function is to remove excess fluid, unneeded electrolytes and wastes from your blood in the form of urine. The ureters carry urine from your kidneys to your bladder, where it's stored until you eliminate it from your body.

Kidney stones form when the components of urine — fluid and various minerals and acids — are out of balance. When this happens, your urine contains more crystal-forming substances, such as calcium and uric acid, than the available fluid can dilute. At the same time, your urine may be short of substances that keep crystals from sticking together and becoming stones. Kidney stones are also prone to develop in highly acidic or highly alkaline urine.

Picture of Kidney Stone

Problems in the way your system absorbs and eliminates calcium and other substances create the conditions for kidney stones to form. Sometimes, the underlying cause is an inherited metabolic disorder or kidney disease. Gout promotes specific types of kidney stones, as does inflammatory bowel disease. So do some drugs, including furosemide (Lasix), used in treating heart failure and high blood pressure; topiramate (Topamax), an anti-seizure drug; and indinavir (Crixivan), which is used to treat human immunodeficiency virus, the cause of AIDS.

kidney stone

What is a kidney stone

A kidney stone is a hard mass developed from crystals that separate from the urine within the urinary tract. Normally, urine contains chemicals that prevent or inhibit the crystals from forming. These inhibitors do not seem to work for everyone, however, so some people form stones. If the crystals remain tiny enough, they will travel through the urinary tract and pass out of the body in the urine without being noticed.
Illustration of percutaneous nephrolithotomy.
Most kidney stones pass out of the body without any intervention by a physician. Stones that cause lasting symptoms or other complications may be treated by various techniques, most of which do not involve major surgery. Also, research advances have led to a better understanding of the many factors that promote stone formation and thus better treatments for preventing stones.

Symptoms

Typical symptoms of heart attack

The typical symptoms of a heart attack are similar to those of angina, but more severe and longer lasting. The victim feels a pain that is usually squeezing or burning or feels a terrible pressure in the middle of chest. This pain may also travel up to the neck, jaw, or shoulder or down the arm and into the back.

Sweating, dizziness, weakness, and shortness of breath often accompany the pain of a heart attack. If you have chest pain that lasts longer than 15 minutes and is not relieved by rest (or by a dose of nitroglycerin), get immediate medical attention.


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In some cases, a heart attack may cause a sensation that feels like indigestion: you get a sick, aching feeling high in the middle of your abdomen. It can cause a feeling of great weakness, or a sense that you are about to faint. (Many of the people who had heart attacks thought that they had intestinal problem instead of associating it with a heart attack).

Risk

Risk of heart attack

You can reduce your risk of having a heart attack—even if you already have coronary heart disease (CHD) or have had a previous heart attack. The key is to take steps to prevent or control your heart disease risk factors.
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Six Key Steps To Reduce Heart Attack Risk

Taking these steps will reduce your risk of having a heart attack:

  1. Stop smoking
  2. Lower high blood pressure
  3. Reduce high blood cholesterol
  4. Aim for a healthy weight
  5. Be physically active each day
  6. Manage diabetes

Causes

Causes of heart attack

Over time, cholesterol buildup can occur in these blood vessels in the form of plaque. This narrows the artery and can restrict the amount of blood that can flow through it. If the artery becomes too narrow, it cannot supply enough blood to the heart muscle when it becomes stressed. Just like arm muscles that begin to hurt if you lift too much, or legs that ache when you run too fast; the heart muscle will ache if it doesn't get adequate blood supply. This ache is called angina.

Picture of Heart Attack (Myocardial Infarction)

If the plaque ruptures, a small blood clot can form within the blood vessel and acutely block the blood flow. When that part of the heart loses its blood supply completely, the muscle dies. This is called a heart attack, or an MI - a myocardial infarction (myo=muscle +cardial=heart; infarction=death due to lack of oxygen).

What is heart attack

A heart attack occurs when blood flow to a section of heart muscle becomes blocked. If the flow of blood isn’t restored quickly, the section of heart muscle becomes damaged from lack of oxygen and begins to die.

Heart attack is a leading killer of both men and women in the United States. But fortunately, today there are excellent treatments for heart attack that can save lives and prevent disabilities. Treatment is most effective when started within 1 hour of the beginning of symptoms. If you think you or someone you’re with is having a heart attack, call 9–1–1 right away.


Heart With Muscle Damage and a Blocked Artery

Figure A shows an overview of the heart and coronary artery.  Figure B shows a cross-section of the coronary artery with plaque buildup and a blood clot.

Figure A is an overview of a heart and coronary artery showing damage (dead heart muscle) caused by a heart attack. Figure B is a cross-section of the coronary artery with plaque buildup and a blood clot.

During a heart attack, if the blockage in the coronary artery isn’t treated quickly, the heart muscle will begin to die and be replaced by scar tissue. This heart damage may not be obvious, or it may cause severe or long-lasting problems.

Symptoms

Symptoms of throat cancer

Unfortunately, some of the early symptoms of throat cancer are fairly general and, therefore, can easily be confused for some other condition or illness. Some of the common symptoms associated with throat cancer include:
  • chronic earaches
  • chronic sore throat
  • difficulty speaking
  • enlarged lymph nodes
  • feelings of numbness in the face
  • hoarse voice
  • pain when swallowing
  • visible sores in the mouth or on the tongue.
Although some may write off these symptoms as a simple sore throat, the flu or even a serious case of the common cold, the key difference between milder conditions and the presence of throat cancer is how long these symptoms last. Chronic or persisting cases of these symptoms can indicate throat cancer.
As a result, if you suffer from any combination of these symptoms, seek medical attention. While you may not have throat cancer, medical attention is necessary to rule out a potentially serious underlying cause.
If you do suffer from throat cancer, early diagnosis of the condition is essential to getting the best results from treatment options. Thus, it is important to understand the symptoms of throat cancer.

Causes

Causes of throat cancer

Throat cancer occurs when cells in your throat develop genetic mutations. These mutations cause cells to grow uncontrollably and continue living after healthy cells would normally die. The accumulating cells can form a tumor in your throat.
Strep Throat Photo
It's not clear what causes the mutation that causes throat cancer. But doctors have identified factors that may increase your risk.

types

Types of thorat cancer

Throat cancer is a general term that applies to cancer that develops in the throat (pharyngeal cancer) or in the voice box (laryngeal cancer). The throat and the voice box are closely connected, with the voice box sitting just below the throat. More specific terms to describe the types of throat cancer include:

  1. Nasopharyngeal cancer begins in the nasopharynx — the part of your throat just behind your nose.
  2. Oropharyngeal cancer begins in the oropharynx — the part of your throat that is right behind your mouth.
  3. Hypopharyngeal cancer (laryngopharyngeal cancer) begins in the hypopharynx (laryngopharynx) — the lower part of your throat, just above your esophagus a nd windpipe.

  4. Glottic cancer begins in the vocal cords.
  5. Supraglottic cancer begins in the upper portion of the larynx and includes cancer that affects the epiglottis, which is a piece of cartilage that blocks food from going into your windpipe.
  6. Subglottic cancer begins in the lower portion of your voice box, below your vocal cords.

What is throat cancer
Your throat is a 5-inch-long muscular tube that begins behind your nose and ends in your neck. Your voice box sits just below your throat and is also susceptible to throat cancer. The voice box is made of cartilage and contains the vocal cords that vibrate to make sound when you talk. Throat cancer can also affect the piece of cartilage (epiglottis) that acts as a lid for your windpipe.














The American Cancer Society estimates that about 24,000 people in the United States are diagnosed with throat cancer each year. About half of those throat cancers occur in the pharynx, with the rest occurring in the larynx.

Treatment of throat cancer

Treatment

Treatment depends on the exact type of cancer, where it is and how far it has spread. Your doctor will discuss your treatment options with you.











Surgery

Surgery is a common way of managing mouth cancer. The aim is to remove the cancer completely. The part of your mouth that the specialist may remove depends on where the cancer is and where it has spread. If the cancer has been found early then it may be very small. This means that it may be possible to have treatment as a day case, with no need to stay overnight in hospital. You may have a local or a general anaesthetic. If the cancer is larger and the surgery is more extensive, you will need to stay in hospital to be treated.

Causes

Causes of mouth cancer

No one knows why some people develop mouth cancer and others don't. However there are certain factors that make mouth cancer more likely. These are listed below.

  • Smoking tobacco - any form of smoking can increase your risk of getting mouth cancer including cigarettes, cigars and pipes, as well as bidis or hand-rolled cigarettes containing cannabis.
  • Chewing tobacco, such as betel quid, gutkha and paan - this tobacco accounts for the high level of mouth cancer found in countries such as India.
  • Drinking excessive alcohol, especially at the same time as smoking or chewing tobacco.
  • Having already had cancer of the head and neck - if you have already had this type of cancer, you are at risk of developing it again.
  • Spending a long time in the sun or under UV light is a risk factor for lip cancer, particularly if you have pale skin.

Other possible risk factors may include:

  • poor diet, lacking vitamins A, C and E and iron, selenium and zinc
  • infection with some strains of the wart virus human papilloma virus (HPV), some strains of which are also linked to cancer of the vulva, cervix and vagina

Mouth cancer can also develop if you have a type of cancer called Kaposi's sarcoma, which can affect any part of the skin. Kaposi's sarcoma is associated with AIDS, a disease that weakens the immune system. It is also associated with a weakened immune system - for example if you are taking medicines to suppress the immune system after a transplant.

Types

Types of mouth cancer
The most common type of mouth cancer is squamous cell carcinoma. It develops from squamous cells - the flat, skin-like cells that cover the lining of the mouth. At least nine out of 10 mouth cancers are squamous cell carcinomas.


Cold Sores Caused by Herpes Simplex Virus








Rarer types of mouth cancer include:

  • salivary gland cancer - this type of cancer starts in the salivary gland cells, which are in the lining of the mouth and throat
  • lymphoma - this type of cancer starts in lymph tissue, which is around the base of the tongue and tonsils
  • melanoma - this is a type of skin cancer that starts in skin pigment cells around the mouth or on the lips.

mouth cancer

Mouth cancer info

Mouth cancer refers to cancer that develops in any of the parts that make up the mouth. Mouth cancer can occur on the lips, gums, tongue,

inside lining of the cheeks, and the roof and floor of the mouth.


hairy tongue







Cancer that occurs on the inside of the mouth is sometimes called oral canceror oral cavity cancer.

Mouth cancer is one of several types of cancer grouped in a category called head and neck cancers. Mouth cancer and other head and neck cancers are often treated similarly.

Treatment

How is bone cancer treated?

There are many different methods available for your doctor to treat bone cancer. The best treatment is based on the type of bone cancer, the location of the cancer, how aggressive the cancer is, and whether or not the cancer has invaded surrounding or distant tissues (metastasized). There are three main types of treatment for bone cancer: surgery, chemotherapy, and radiation therapy. These can be used either individually or combined with each other

Surgery is often used to treat bone cancer. The goal of surgery is usually to remove the entire tumor and a surrounding area of normal bone. After the tumor has been removed, a pathologist examines it to determine if there is normal bone completely surrounding the tumor. If a portion of the cancer is left behind, it can continue to grow and spread, requiring further treatment. Historically, amputations were frequently used to remove bone cancer. Newer techniques have decreased the need for amputation. In many cases, the tumor can be removed with a rim of normal bone without the need for an amputation. Depending on the amount of bone removed, the surgeon will replace something in its location. For smaller areas, this may be either bone cement or a bone graft from another place in your body or from the bone bank. For larger areas, the surgeon may place larger grafts from the bone bank or metal implants. Some of these metal implants have the ability to lengthen when used in growing children.

You may be referred to a medical oncologist for chemotherapy. This is the use of various medications used to try to stop the growth of the cancer cells. Chemotherapy can be used prior to surgery to try to shrink the bone tumor to make surgery easier. It can also be used after surgery to try to kill any remaining cancer cells left following surgery.

You could also be referred to a radiation oncologist for radiation therapy. The radiation therapy uses high-energy x-ray aimed at the site of the cancer to try to kill the cancer cells. This treatment is given in small doses daily over a period of days to months.

risk of bone cancer

Bone marrow transplantation

Osteosarcoma has been reported in a few patients who have undergone bone marrow (stem cell) transplantation.

Injuries

People have wondered whether injury to a bone can cause cancer, but this has never been proven. Many people with bone cancer remember having hurt that part of their bone. Most doctors believe that this did not cause the cancer, but that the cancer caused them to remember the incident, or that the injury drew their attention to that bone and caused them to notice a problem that had already been present for some time.

Radiation

Bone exposure to radiation may also increase the risk of developing bone cancer. A typical x-ray of a bone is not dangerous, but exposure to large doses of radiation does pose a risk. For example, radiation therapy to treat cancer can cause a new cancer to develop in one of the bones in the treatment area. Being treated at a younger age and/or being treated with higher doses of radiation (usually over 60 Gy) increases the risk of developing bone cancer. Exposure to radioactive materials such as radium and strontium can also cause bone cancer because these minerals build up in bones. Non-ionizing radiation, such as microwaves, electromagnetic fields from power lines, cellular phones, and household appliances, does not increase bone cancer risk.

Risk

Risk of bone cancer
A risk factor is anything that affects your chance of getting a disease such as cancer. Different cancers have different risk factors. For example, exposing skin to strong sunlight is a risk factor for skin cancer. Smoking is a risk factor for cancers of the lung, mouth, larynx, bladder, kidney, and several other organs. But having a risk factor, or even several, does not mean that you will get the disease. Most people with bone cancers do not have any apparent risk factors.

Genetic disorders

A very small number of bone cancers (especially osteosarcomas) appear to be hereditary.

Osteosarcoma

Children with certain rare inherited syndromes have an increased risk of developing osteosarcoma.


  1. The Li-Fraumeni syndrome makes people much more likely to develop several types of cancer, including breast cancer, brain cancer, osteosarcoma, and other types of sarcoma. Most of those cases are caused by a mutation of the p53 tumor suppressor gene, but some are caused by mutations in the gene CHEK2.
  2. Another syndrome that includes bone cancer is the Rothmund-Thompson syndrome. Children with this syndrome are short, have skeletal problems, and rashes. They also are more likely to develop osteosarcoma. This syndrome is caused by abnormal changes in the gene REQL4.
  3. Retinoblastoma is a rare eye cancer of children that can be hereditary. The inherited form of retinoblastoma is caused by a mutation (abnormal copy) of the RB1 gene. Those with this mutation also have an increased risk of developing bone or soft tissue sarcomas. Also, if radiation therapy is used to treat the retinoblastoma, the risk of osteosarcoma in the bones around the eye is even higher.

Finally, there are families with several members that have developed osteosarcoma without inherited changes in any of the known genes. The gene defects that may cause cancers in these families haven't been discovered yet.

Types

Types of Bone Cancer
Bones serve various purposes in the body. They protect and support the organs in the body. For instance, the brain is protected by the skull and the lungs are protected by the ribs. Blood cells are made and stored in the bone marrow, the spongy and soft tissue that many bone have in their center.

Primary bone cancer occurs most commonly in the legs and arms, although it can also affect other bones of the body. Primary bone cancers are usually referred to as sarcomas, of which there are several types. Each type of sarcoma affects a different type of bone tissue, with the most common being: chondrosarcoma; Ewing’s sarcoma; and osteosarcoma.
Chondrosarcoma: This type of bone cancer occurs mostly in adults. It affects the cartilage, which is the rubber-like tissue that is around the joints.

Ewing's sarcoma: This bone cancer occurs most often amongst people between the ages of 10-25, with teenagers being most affected. It affects the shaft, or middle part of large bones. It usually occurs in the long bones of the upper arm and thigh and also the hipbones. It can also affect the ribs.

Osteosarcoma: This is the most common kind of bone cancer and it affects young people in the age group of 10-25 years. Males are more susceptible to it compared to females. Osteosarcoma usually begins where new bone tissue forms, at the ends of bones, as young people grow. The long bones of the legs and arms are usually affected by it.

Cancers like the above, which start in the bone, occur rarely. However, it is quite common for cancers to spread from the other parts of the body to the bone. This type of cancer is known as metastatic cancer. Around 80% of the metastatic cancers that affect the bone are due to primary carcinomas that affect other organs such as the prostate, breast, kidney, lung, stomach, pancreas, and thyroid. Each of these types of metastatic cancers, which affect the bone, is named according to the tissue or organ where the primary cancer occurs.

Symptoms

Symptoms of bone cancer
The symptoms of bone cancer vary from one person to another according to the location and size of the bone cancer. Pain is one of the most common bone cancer symptoms. Generally, there is a gradual increase in the severity of the symptoms with time. At first, the pain may only be felt with activity or at night. According to the growth of the cancerous tumor, people may experience the symptoms for weeks, perhaps even months, sometimes even years until they seek medical help. Sometimes a lump or mass may occur either in the tissues that surround the bone or on the bone itself. This commonly occurs with fibrosarcoma or MFH, but can also occur with other types of bone tumors as well. Some of the less common bone cancer symptoms are weight loss, night sweats, chills, and fever. These symptoms usually occur when the cancerous tumor spreads to the other parts of the body.
Bone Cancer Symptoms
Various factors affect the successful treatment of bone cancer, one of the most important being the early detection of the symptoms of bone cancer. Moreover, the recovery from this disease is largely dependent on the recognition and understanding of bone cancer symptoms. These symptoms are actually signs warning that something could be wrong. Hence, these symptoms of bone cancer should not be ignored. And, even though the symptoms may ultimately prove to be the root causes of some other ailment, it is better to make certain and not ignore these bone cancer symptoms.

 
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