liver cancer

Cancers that start in the liver

Several types of cancer can start in the liver.

hepatocellular carcinoma: This is the most common form of liver cancer in adults. It begins in the hepatocytes the main type of liver cell. About 3 out of 4 cancers that start in the liver are this type. Most of the information in this article refers to hepatocellular cancer.

This type of cancer can have different growth patterns.

• Some begin as a single tumor that grows larger. Only late in the disease does it spread to other parts of the liver.

• This type of cancer may also begin in many spots throughout the liver, not as a single tumor. This is most often seen in people with cirrhosis and is the most common pattern seen in the United States.

Doctors can figure out the subtypes of hepatocellular cancer by looking at the cancer under a microscope. Most of these subtypes do not affect treatment or the patient's outlook. But one rare type, called fibrolamellar, has a much better outlook (prognosis) than other forms of liver cancer.

hepatoblastoma: There is a very rare kind of liver cancer that develops in children. It is usually found in children younger than 4 years old. About 70% of children with this disease are treated successfully with surgery and chemotherapy. The survival rate is greater than 90% for early-stage disease.