Ewing's sarcoma is a form of bone  cancer that is typically found in teenagers as they undergo growth  spurts; but it can occur at any age. Early detection is key to surviving  this aggressive type of bone cancer. Signs and symptoms, such as pain  and swelling or unexplained fever and weight loss, should be checked out  by a doctor immediately.                                       
In the United States, 250 children and adolescents are  diagnosed with Ewing's sarcoma each year. Although it accounts for only  about 3 percent of all childhood cancers, Ewing's sarcoma is the second  most common malignant bone cancer in children. In about one-third of  those diagnosed with Ewing's sarcoma, the cancer has spread to other  areas of the body by the time it’s diagnosed. When this happens, the  five-year survival rate is less than 30 percent. 
Ewing's sarcoma  usually appears in the middle of the long bones of the arms and legs, or  in the bones of the pelvis, and often invades the muscle and soft  tissue located next to the tumor site. This type of bone cancer also can  spread to other parts of the body, including the bone marrow, other  bones, lungs, kidneys, and the adrenal gland. Sometimes the tumor  remains in the soft tissues of the body and does not involve bone at  all. 
Ewing's Sarcoma: Causes and Symptoms
Genetics play a major role in Ewing's sarcoma. Nine out of 10 people  diagnosed with Ewing's sarcoma have a genetic abnormality that makes  them susceptible. 
There are no screening tests to detect early  signs of bone cancer, including Ewing's sarcoma. The best way to detect  Ewing's sarcoma in its earliest stage is to be mindful of its symptoms,  which may include:
- pain at or near the site of the tumor
- swelling and redness near the tumor
- fever for no reason
- a bone that breaks unexpectedly and without apparent reason
- weight loss or reduced appetite
Pain is usually the most significant symptom of Ewing's sarcoma. Since  many of these symptoms may be attributed to an injury, a muscle strain,  or other illnesses or conditions, it's important that you see a doctor  as soon as possible if pain persists.