Causes

Causes of kidney stones

Your kidneys are two bean-shaped organs, each about the size of your fist. They're located in back of your abdomen on each side of your spine, and their main function is to remove excess fluid, unneeded electrolytes and wastes from your blood in the form of urine. The ureters carry urine from your kidneys to your bladder, where it's stored until you eliminate it from your body.

Kidney stones form when the components of urine — fluid and various minerals and acids — are out of balance. When this happens, your urine contains more crystal-forming substances, such as calcium and uric acid, than the available fluid can dilute. At the same time, your urine may be short of substances that keep crystals from sticking together and becoming stones. Kidney stones are also prone to develop in highly acidic or highly alkaline urine.

Picture of Kidney Stone

Problems in the way your system absorbs and eliminates calcium and other substances create the conditions for kidney stones to form. Sometimes, the underlying cause is an inherited metabolic disorder or kidney disease. Gout promotes specific types of kidney stones, as does inflammatory bowel disease. So do some drugs, including furosemide (Lasix), used in treating heart failure and high blood pressure; topiramate (Topamax), an anti-seizure drug; and indinavir (Crixivan), which is used to treat human immunodeficiency virus, the cause of AIDS.

kidney stone

What is a kidney stone

A kidney stone is a hard mass developed from crystals that separate from the urine within the urinary tract. Normally, urine contains chemicals that prevent or inhibit the crystals from forming. These inhibitors do not seem to work for everyone, however, so some people form stones. If the crystals remain tiny enough, they will travel through the urinary tract and pass out of the body in the urine without being noticed.
Illustration of percutaneous nephrolithotomy.
Most kidney stones pass out of the body without any intervention by a physician. Stones that cause lasting symptoms or other complications may be treated by various techniques, most of which do not involve major surgery. Also, research advances have led to a better understanding of the many factors that promote stone formation and thus better treatments for preventing stones.

Symptoms

Typical symptoms of heart attack

The typical symptoms of a heart attack are similar to those of angina, but more severe and longer lasting. The victim feels a pain that is usually squeezing or burning or feels a terrible pressure in the middle of chest. This pain may also travel up to the neck, jaw, or shoulder or down the arm and into the back.

Sweating, dizziness, weakness, and shortness of breath often accompany the pain of a heart attack. If you have chest pain that lasts longer than 15 minutes and is not relieved by rest (or by a dose of nitroglycerin), get immediate medical attention.


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In some cases, a heart attack may cause a sensation that feels like indigestion: you get a sick, aching feeling high in the middle of your abdomen. It can cause a feeling of great weakness, or a sense that you are about to faint. (Many of the people who had heart attacks thought that they had intestinal problem instead of associating it with a heart attack).

Risk

Risk of heart attack

You can reduce your risk of having a heart attack—even if you already have coronary heart disease (CHD) or have had a previous heart attack. The key is to take steps to prevent or control your heart disease risk factors.
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Six Key Steps To Reduce Heart Attack Risk

Taking these steps will reduce your risk of having a heart attack:

  1. Stop smoking
  2. Lower high blood pressure
  3. Reduce high blood cholesterol
  4. Aim for a healthy weight
  5. Be physically active each day
  6. Manage diabetes

Causes

Causes of heart attack

Over time, cholesterol buildup can occur in these blood vessels in the form of plaque. This narrows the artery and can restrict the amount of blood that can flow through it. If the artery becomes too narrow, it cannot supply enough blood to the heart muscle when it becomes stressed. Just like arm muscles that begin to hurt if you lift too much, or legs that ache when you run too fast; the heart muscle will ache if it doesn't get adequate blood supply. This ache is called angina.

Picture of Heart Attack (Myocardial Infarction)

If the plaque ruptures, a small blood clot can form within the blood vessel and acutely block the blood flow. When that part of the heart loses its blood supply completely, the muscle dies. This is called a heart attack, or an MI - a myocardial infarction (myo=muscle +cardial=heart; infarction=death due to lack of oxygen).

What is heart attack

A heart attack occurs when blood flow to a section of heart muscle becomes blocked. If the flow of blood isn’t restored quickly, the section of heart muscle becomes damaged from lack of oxygen and begins to die.

Heart attack is a leading killer of both men and women in the United States. But fortunately, today there are excellent treatments for heart attack that can save lives and prevent disabilities. Treatment is most effective when started within 1 hour of the beginning of symptoms. If you think you or someone you’re with is having a heart attack, call 9–1–1 right away.


Heart With Muscle Damage and a Blocked Artery

Figure A shows an overview of the heart and coronary artery.  Figure B shows a cross-section of the coronary artery with plaque buildup and a blood clot.

Figure A is an overview of a heart and coronary artery showing damage (dead heart muscle) caused by a heart attack. Figure B is a cross-section of the coronary artery with plaque buildup and a blood clot.

During a heart attack, if the blockage in the coronary artery isn’t treated quickly, the heart muscle will begin to die and be replaced by scar tissue. This heart damage may not be obvious, or it may cause severe or long-lasting problems.

Symptoms

Symptoms of throat cancer

Unfortunately, some of the early symptoms of throat cancer are fairly general and, therefore, can easily be confused for some other condition or illness. Some of the common symptoms associated with throat cancer include:
  • chronic earaches
  • chronic sore throat
  • difficulty speaking
  • enlarged lymph nodes
  • feelings of numbness in the face
  • hoarse voice
  • pain when swallowing
  • visible sores in the mouth or on the tongue.
Although some may write off these symptoms as a simple sore throat, the flu or even a serious case of the common cold, the key difference between milder conditions and the presence of throat cancer is how long these symptoms last. Chronic or persisting cases of these symptoms can indicate throat cancer.
As a result, if you suffer from any combination of these symptoms, seek medical attention. While you may not have throat cancer, medical attention is necessary to rule out a potentially serious underlying cause.
If you do suffer from throat cancer, early diagnosis of the condition is essential to getting the best results from treatment options. Thus, it is important to understand the symptoms of throat cancer.

 
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